Proton pump inhibitors and hypomagnesemia monitoring
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منابع مشابه
Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors
In 2006, hypomagnesemia was first described as a complication of proton-pump inhibitors. To address this issue, we systematically reviewed the literature. Hypomagnesemia, mostly associated with hypocalcemic hypoparathyroidism and hypokalemia, was reported in 64 individuals on long-term proton-pump inhibitors. Hypomagnesemia recurred following replacement of one proton-pump inhibitor with anothe...
متن کاملHypomagnesemia and proton-pump inhibitors.
INTRODUCTION Proton pump inhibitors (PPIs) have been linked to clinically symptomatic hypomagnesemia. AREAS COVERED We searched Medline database in all languages using 'proton-pump inhibitors, magnesium, hypomagnesemia and hypomagnesemic hypoparathyroidism' as search terms and other articles were identified through searches of the files of the authors and reference lists from relevant article...
متن کاملHypomagnesemia in hemodialysis patients: role of proton pump inhibitors.
BACKGROUND Recent observations have associated hypomagnesemia with increased risk of cardiovascular morbidity and mortality in hemodialysis patients. METHODS We did a 3-month chart review of 62 chronic hemodialysis patients at a single US hospital. All were dialyzed using a dialysate [Mg] of 0.75-1.0 mEq/l. Patients were divided into two groups: hypomagnesemic (mean predialysis plasma [Mg] <1...
متن کاملThe Association between the Use of Proton Pump Inhibitors and the Risk of Hypomagnesemia: A Systematic Review and Meta-Analysis
BACKGROUND Although many case reports have described patients with proton pump inhibitor (PPI)-induced hypomagnesemia, the impact of PPI use on hypomagnesemia has not been fully clarified through comparative studies. We aimed to evaluate the association between the use of PPI and the risk of developing hypomagnesemia by conducting a systematic review with meta-analysis. METHODS We conducted a...
متن کاملUse of Proton Pump Inhibitors is Associated withSevere Hypomagnesemia in Kidney TransplantRecipients
Hypomagnesemia is common in the early post-transplant period and is often associated with CNI use. PPIs are preferred choice of agents for stress ulcer prophylaxis and have been associated with hypomagnesemia especially when coupled with diuretic use. We postulated that PPI use in the post-transplant setting increases the severity of hypomagnesemia associated with CNI use compared to H2B. A tot...
متن کاملCommon single nucleotide polymorphisms in transient receptor potential melastatin type 6 increase the risk for proton pump inhibitor-induced hypomagnesemia: a case-control study.
OBJECTIVE Proton pump inhibitors (PPIs) are effective drugs for the treatment of gastric acid-related disorders. Serious adverse events are rare for PPIs, but recent data suggest that PPIs cause hypomagnesemia. The aim of this study was to estimate the frequency of PPI-induced hypomagnesemia and to define the risk factors for its development. MATERIALS AND METHODS A total of 133 chronic users...
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